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Healthcare Data GlossaryData Standards

DRG: Definition and Healthcare Context

Full name: Diagnosis Related Group

A Diagnosis Related Group (DRG) is a patient classification system that groups similar hospital inpatient cases into categories that are clinically coherent and resource-intensive. CMS uses Medicare Severity DRGs (MS-DRGs) to determine prospective payment amounts for hospital inpatient stays under Medicare Part A through the Inpatient Prospective Payment System (IPPS). Each DRG is assigned a relative weight representing average resource consumption. Hospitals receive a fixed payment per DRG regardless of actual costs.

Last updated: 2026-06-17Reviewed by: Dr. Jennifer Montecillo, MD — Gullas College of Medicine, 2019. Non-practicing medical reviewer.

How it’s used

  • Healthcare Cost Report Information System (HCRIS): hospital cost reports include total Medicare inpatient discharges by DRG, enabling financial analysis by case-mix.
  • CMS Care Compare — Hospitals: hospital quality measures include risk-adjusted readmission and mortality rates calculated at the DRG and condition level.

Frequently asked questions

What is a DRG?
A DRG (Diagnosis Related Group) is a patient classification system used by CMS to set prospective payment rates for Medicare inpatient hospital stays.
What is an MS-DRG?
MS-DRG stands for Medicare Severity DRG — the version of DRGs used for Medicare inpatient payment that accounts for patient severity of illness.
How does DRG-based payment work?
Under IPPS, hospitals receive a fixed payment per admission based on the assigned DRG and its relative weight, regardless of the actual costs incurred.

Related terms

  • ICD-10
  • HCPCS
  • CPT Code
  • HCRIS
  • CMS
  • Medicare

Authoritative sources

  • CMS: Inpatient Prospective Payment System (IPPS) and MS-DRGs↗
  • CMS: MS-DRG Classification and Software↗
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Reviewed by Jennifer Montecillo, MD, medical reviewer. Non-practicing medical reviewer.

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Reviewed by Jennifer Montecillo, MD, medical reviewer. Non-practicing medical reviewer.

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